This paper reports full-scale tests on threaded connections used in drill strings. A concise background is given concerning the in-service environment and loading conditions on the connections. This details some of the reasons particular steels are used in preference to others. Crack growth data is given for ten full-scale axial and rotating bend tests. This is compared with predictions from a dedicated weight function fracture mechanics solution designed for threaded connections. Crack aspect ratio is considered with a view to development of an appropriate empirical model.