In literature, the continuous line bucket lifting system and the pipe lifting system, as two typical mineral lifting methods in deep sea mining systems, have been discussed since the 60s of the last century. The purpose of this paper is to determine an appropriate lifting method for deep sea mining systems at different working conditions. The determination is based on the comparison of the analysis results of the two typical lifting methods considering the technology performance and the profitability. The analysis is based on a numerical calculation performed in a Matlab environment. This paper shows the comparison of the results of the continuous line bucket system and pipe lifting system in terms of the lifting efficiency, the energy consumption, and the profitability. The research reported on this paper can be utilized to select a proper lifting method for a deep sea mining project depending on its specific criteria analysis.