Cyclone venturi dryer is suitable for drying materials with large particle size and wide distribution. The working process of cyclone venturi dryer is a very complicated three-dimensional and turbulent motion, so it is difficult to be studied theoretically and experimentally. In order to study the internal flow characteristics of the biomass particle cyclone venturi dryer, the computational fluid dynamics (CFD) software was used to simulate the gas-solid two-phase flow field inside the cyclone venturi dryer. The continuous phase adopts the Realizable k-ε turbulence model and the particle phase is discrete. The effects of different injection volume on the pressure, velocity, and temperature fields inside a cyclone venturi dryer were analyzed. The results showed that the maximum pressure drop and velocity change inside the dryer were at the venturi pipe. The wet material of the cyclone venturi dryer was inhaled into the venturi contraction tube by the negative pressure formed after the highspeed airflow was ejected, thus the mixture was completed in the venturi throat. The wood debris material was mixed with the high-speed hot gas flow in the venturi throat and then sprayed into the diffusion pipe. In the diffusion pipe of venturi, the heat and mass transfer process of wet wood debris and heat flow in venturi diffusion tube was completed. It is in good agreement with the simulation results. This study can provide a reference for the optimization design of the related cyclone venturi dryer structure.