Magnetic-nanoparticles cancer hyperthermia, a side effects-free, potential cancer therapy employing magnetic nanoparticle remotely heated by alternating magnetic field (AMF), is receiving considerable attention from researchers and physicians [1–3]. Specific absorption rate (SAR), which is used to quantify nanoparticles’ heat generation under the applied AMF, is defined as the thermal power per unit mass dissipated by the magnetic material . SAR depends on field parameters (magnetic field strength and frequency) and material system (size and magnetic properties of nanoparticles). Accurate measurement of SAR is a critical step in enabling comparison with theoretical predictions for understanding other parameters that may affect the heat generation rate such as nanoparticle functionalization, clustering and immobilization in biological medium . A main drawback is the fact that independent measurements on similar samples often provide significantly different SAR values. For example, the reported SAR of magnetite-based aqueous solution Endorem commercially available from Guerbet greatly differs among Ref. ,  and , even when factors such as field intensity, H, and frequency, f, are taken into account.
- Fluids Engineering Division
Sources of Experimental Errors in Specific Absorption Rate Measurement of Magnetic Nanoparticles
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Huang, S, Gupta, A, & Borca-Tasciuc, D. "Sources of Experimental Errors in Specific Absorption Rate Measurement of Magnetic Nanoparticles." Proceedings of the ASME 2010 8th International Conference on Nanochannels, Microchannels, and Minichannels collocated with 3rd Joint US-European Fluids Engineering Summer Meeting. ASME 2010 8th International Conference on Nanochannels, Microchannels, and Minichannels: Parts A and B. Montreal, Quebec, Canada. August 1–5, 2010. pp. 731-732. ASME. https://doi.org/10.1115/FEDSM-ICNMM2010-30796
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