We examined glioma tissues immediately after en-bloc removal during surgery and measured elastic modulus, viscosity, and viscoelasticity of the gray and white matter to confirm the feasibility of measurement using an indentation device. Measurements were obtained from excised parenchymal brain tumor tissue of four adult patients. The white matter exhibited higher elastic modulus than the gray matter in all patients. Viscoelasticity analysis was performed in two patients, with viscoelastic behavior observed in the white but not in the gray matter in both patients. The loss of viscoelasticity in the white matter observed in one patient may be related to the calcification visible in the preoperative computed tomography image.
Measurement of Glioma Viscoelasticity Using a Handheld Palpation Imitation Device
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Hayashi, S, Sakuma, A, Sasayama, T, & Kohmura, E. "Measurement of Glioma Viscoelasticity Using a Handheld Palpation Imitation Device." Proceedings of the ASME 2017 International Mechanical Engineering Congress and Exposition. Volume 3: Biomedical and Biotechnology Engineering. Tampa, Florida, USA. November 3–9, 2017. V003T04A008. ASME. https://doi.org/10.1115/IMECE2017-70835
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